Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C19 (Homo sapiens (Human)) | BDBM50353392 (CHEMBL1829761 | US8575157, 197 | US8592410, Compar...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | US Patent | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharmaceuticals, Inc.; Boehringer Ingelheim International GmbH US Patent | Assay Description Using a procedure similar to that described in Biological Test Example 6, the inhibition of cytochrome P450 2C19-isoenzyme catalysed N-demethylation ... | US Patent US8592410 (2013) BindingDB Entry DOI: 10.7270/Q2CF9NRN | |||||||||||
More data for this Ligand-Target Pair |