Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Northeastern University Curated by ChEMBL | Assay Description Agonistic activity against calf striatal Dopamine receptor using [3H]- ADTN radioligand | J Med Chem 33: 1800-5 (1990) BindingDB Entry DOI: 10.7270/Q2K35SMD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates. | J Med Chem 25: 990-2 (1982) BindingDB Entry DOI: 10.7270/Q27P91K4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates. | J Med Chem 25: 990-2 (1982) BindingDB Entry DOI: 10.7270/Q27P91K4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei. | J Med Chem 23: 977-80 (1980) BindingDB Entry DOI: 10.7270/Q2N3005S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 8.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding to dopamine receptor using [3H]spiroperidol as radioligand in calf caudate nucleus homogenates. | J Med Chem 25: 990-2 (1982) BindingDB Entry DOI: 10.7270/Q27P91K4 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity was evaluated against [3H]dopamine (DA) calf caudate dopamine receptor | J Med Chem 28: 1540-2 (1985) BindingDB Entry DOI: 10.7270/Q27M0B5C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Noncompetitive Iinhibitory activity against human liver DHPR enzyme | J Med Chem 28: 367-75 (1985) BindingDB Entry DOI: 10.7270/Q22V2J98 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei. | J Med Chem 23: 977-80 (1980) BindingDB Entry DOI: 10.7270/Q2N3005S | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain. | J Med Chem 25: 1442-6 (1982) BindingDB Entry DOI: 10.7270/Q2XD13WD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against rat striatal synaptosomes Dihydrodipicolinate reductase (DHPR) | J Med Chem 28: 367-75 (1985) BindingDB Entry DOI: 10.7270/Q22V2J98 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 1.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro inhibitory activity was evaluated against [3H]spiperone calf caudate (SPC) dopamine receptor | J Med Chem 28: 1540-2 (1985) BindingDB Entry DOI: 10.7270/Q27M0B5C | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM50001955 ((-)6-Methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]qu...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain. | J Med Chem 25: 1442-6 (1982) BindingDB Entry DOI: 10.7270/Q2XD13WD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |