Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding to dopamine receptor using [3H]- ADTN as radioligand in calf caudate nucleus homogenates. | J Med Chem 25: 990-2 (1982) BindingDB Entry DOI: 10.7270/Q27P91K4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding to dopamine receptor using [3H]apomorphine as radioligand in calf caudate nucleus homogenates. | J Med Chem 25: 990-2 (1982) BindingDB Entry DOI: 10.7270/Q27P91K4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]dopamine binding to Dopamine receptor in calf caudate nuclei. | J Med Chem 23: 977-80 (1980) BindingDB Entry DOI: 10.7270/Q2N3005S | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory binding activity against dopamine receptor using [3H]ADTN as the radioligand in striatal tissue of calf brain. | J Med Chem 25: 1442-6 (1982) BindingDB Entry DOI: 10.7270/Q2XD13WD | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of [3H]haloperidol binding to Dopamine receptor in calf caudate nuclei. | J Med Chem 23: 977-80 (1980) BindingDB Entry DOI: 10.7270/Q2N3005S | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for binding to dopamine receptor using [3H]spiroperidol as radioligand in calf caudate nucleus homogenates. | J Med Chem 25: 990-2 (1982) BindingDB Entry DOI: 10.7270/Q27P91K4 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
D(1A)/D(2) dopamine receptor (BOVINE) | BDBM55121![]() (3-HYDROXYTYRAMINE HYDROCHLORIDE | 4-(2-aminoethyl)...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid PDB UniChem Similars | PDB PubMed | n/a | n/a | 1.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory binding activity against dopamine receptor using [3H]spiperone as the radioligand in striatal tissue of calf brain. | J Med Chem 25: 1442-6 (1982) BindingDB Entry DOI: 10.7270/Q2XD13WD | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |