Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM194810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM194810 (US9206167, 32 | USRE48059, Compound of Example 32) Show SMILES CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O Show InChI InChI=1S/C26H31N3O2S/c1-27-12-9-20-7-8-21(19-23(20)26(27)30)31-17-3-2-11-28-13-15-29(16-14-28)24-5-4-6-25-22(24)10-18-32-25/h4-8,10,18-19H,2-3,9,11-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	-50.4	n/a	n/a	n/a	n/a	n/a	7.4	25
OTSUKA PHARMACEUTICAL CO., LTD. US Patent					Assay Description The assay was performed according to the method by Kohler et al. (Kohler C, Hall H, Ogren S O and Gawell L, Specific in vitro and in vivo binding of ...				US Patent US9206167 (2015) BindingDB Entry DOI: 10.7270/Q2XD10GS
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM194810 (US9206167, 32 | USRE48059, Compound of Example 32) Show SMILES CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O Show InChI InChI=1S/C26H31N3O2S/c1-27-12-9-20-7-8-21(19-23(20)26(27)30)31-17-3-2-11-28-13-15-29(16-14-28)24-5-4-6-25-22(24)10-18-32-25/h4-8,10,18-19H,2-3,9,11-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Otsuka Pharmaceutical Co., Ltd. US Patent					Assay Description Dopamine D2: The binding assay was performed using 40 μl of the membrane specimen, 20 μl of [3H]-raclopride (final concentration 1 to 2 nM)...				US Patent USRE48059 (2020) BindingDB Entry DOI: 10.7270/Q2833W3C
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM194810 (US9206167, 32 | USRE48059, Compound of Example 32) Show SMILES CN1CCc2ccc(OCCCCN3CCN(CC3)c3cccc4sccc34)cc2C1=O Show InChI InChI=1S/C26H31N3O2S/c1-27-12-9-20-7-8-21(19-23(20)26(27)30)31-17-3-2-11-28-13-15-29(16-14-28)24-5-4-6-25-22(24)10-18-32-25/h4-8,10,18-19H,2-3,9,11-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]spiperone from D2 receptor in rat striatum measured after 15 mins by liquid scintillation counting method				Citation and Details Article DOI: 10.1016/j.ejmech.2020.112709 BindingDB Entry DOI: 10.7270/Q2XK8K6M
					More data for this Ligand-Target Pair