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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50000632'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50000632
PNG
(1-{1-[6-(4-Oxo-2-phenyl-4H-chromen-6-yloxy)-hexyl]...)
Show SMILES O=c1[nH]c2ccccc2n1C1CCN(CCCCCCOc2ccc3oc(cc(=O)c3c2)-c2ccccc2)CC1
Show InChI InChI=1S/C33H35N3O4/c37-30-23-32(24-10-4-3-5-11-24)40-31-15-14-26(22-27(30)31)39-21-9-2-1-8-18-35-19-16-25(17-20-35)36-29-13-7-6-12-28(29)34-33(36)38/h3-7,10-15,22-23,25H,1-2,8-9,16-21H2,(H,34,38)
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PC cid
PC sid
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 220n/an/an/an/an/an/an/an/a



Nova Pharmaceutical Corporation

Curated by ChEMBL


Assay Description
Affinity towards dopamine receptor D2 site was determined by competition studies using [3H]-sulpiride in rat striatum.

J Med Chem 35: 1526-35 (1992)


BindingDB Entry DOI: 10.7270/Q2XG9Q38
More data for this
Ligand-Target Pair