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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50002325'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50002325
PNG
(2-{4-[3,4-Bis-(4-fluoro-phenyl)-but-3-enyl]-pipera...)
Show SMILES Fc1ccc(\C=C(/CCN2CCN(CC2)c2ncccn2)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C24H24F2N4/c25-22-6-2-19(3-7-22)18-21(20-4-8-23(26)9-5-20)10-13-29-14-16-30(17-15-29)24-27-11-1-12-28-24/h1-9,11-12,18H,10,13-17H2/b21-18+
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PubMed
n/an/a 1.70E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
In vitro inhibitory against radioligand [3H]spiperone binding to rat striatal Dopamine receptor D2

J Med Chem 35: 4516-25 (1993)


BindingDB Entry DOI: 10.7270/Q2H70GDV
More data for this
Ligand-Target Pair