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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50002327'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50002327
PNG
(3-(4-Fluoro-phenyl)-6-(4-pyrimidin-2-yl-piperazin-...)
Show SMILES CCC(O)(CCCN1CCN(CC1)c1ncccn1)c1ccc(F)cc1
Show InChI InChI=1S/C20H27FN4O/c1-2-20(26,17-5-7-18(21)8-6-17)9-3-12-24-13-15-25(16-14-24)19-22-10-4-11-23-19/h4-8,10-11,26H,2-3,9,12-16H2,1H3
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n/an/a 415n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
In vitro inhibitory against radioligand [3H]spiperone binding to rat striatal Dopamine receptor D2

J Med Chem 35: 4516-25 (1993)


BindingDB Entry DOI: 10.7270/Q2H70GDV
More data for this
Ligand-Target Pair