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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50002336'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50002336
PNG
(2-(4-Fluoro-phenyl)-5-[4-(5-fluoro-pyrimidin-2-yl)...)
Show SMILES CC(O)(CCCN1CCN(CC1)c1ncc(F)cn1)c1ccc(F)cc1
Show InChI InChI=1S/C19H24F2N4O/c1-19(26,15-3-5-16(20)6-4-15)7-2-8-24-9-11-25(12-10-24)18-22-13-17(21)14-23-18/h3-6,13-14,26H,2,7-12H2,1H3
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PC sid
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PubMed
n/an/a 2.12E+3n/an/an/an/an/an/a



Bristol-Myers Squibb Co.

Curated by ChEMBL


Assay Description
In vitro inhibitory against radioligand [3H]spiperone binding to rat striatal Dopamine receptor D2

J Med Chem 35: 4516-25 (1993)


BindingDB Entry DOI: 10.7270/Q2H70GDV
More data for this
Ligand-Target Pair