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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50029263'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50029263
PNG
(N-Isopropyl-N-{5-[4-(2-methoxy-phenyl)-piperazin-1...)
Show SMILES COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)C(C)=O)n2C)CC1
Show InChI InChI=1S/C23H34N4O2/c1-18(2)27(19(3)28)17-21-11-10-20(24(21)4)16-25-12-14-26(15-13-25)22-8-6-7-9-23(22)29-5/h6-11,18H,12-17H2,1-5H3
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Similars
PubMed
 30n/an/an/an/an/an/an/an/a



R. W. Johnson Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Binding affinity was determined against Dopamine receptor D2 using [3H]spiperone

J Med Chem 38: 4198-210 (1995)


BindingDB Entry DOI: 10.7270/Q2GX4C61
More data for this
Ligand-Target Pair