BindingDB PrimarySearch

Found 9 hits Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50041961'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Compound was tested for agonistic activity against D2 receptor from cloned CHO cells, used [3H]U-86170 as radioligand				J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding affinity for sigma receptor using 2 nM of [3H]-DTG as radioligand, in membranes from brain minus cerebellum				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
University of Göteborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Binding affinity of the compound was measured at cloned mammalian dopamine D2 receptor expressed in CHO-K1 cells (using [3H]-U-86,170)				Bioorg Med Chem Lett 4: 689-694 (1994) Article DOI: 10.1016/S0960-894X(01)80181-5 BindingDB Entry DOI: 10.7270/Q2SX6D5J
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Tested in vitro for the inhibition of [3H]-raclopride binding to Dopamine receptor D2 in rat striatum				Bioorg Med Chem Lett 7: 2759-2764 (1997) Article DOI: 10.1016/S0960-894X(97)10068-3 BindingDB Entry DOI: 10.7270/Q2F47P56
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (BOVINE)	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Evaluated for binding towards Dopamine receptor D2 using [3H]-spiperone as radioligand, in cloned mammalian receptors expressed in CHO-K1 cells				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
University of Göteborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Upjohn Laboratories Curated by ChEMBL					Assay Description Compound was tested for antagonistic activity against D2 receptor from rat striatum, used [3H]raclopride as radioligand				J Med Chem 36: 1301-15 (1993) BindingDB Entry DOI: 10.7270/Q2TD9Z06
Upjohn Laboratories Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars		63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity against human Dopamine receptor D2 in mouse LtK- cells using [3H]spiperone.				Citation and Details BindingDB Entry DOI: 10.7270/Q2VQ34VM
TBA					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Binding towards Dopamine receptor D3 expressed in CHO-K1 cells using [3H]spiperone				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
University of Göteborg Curated by ChEMBL					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50041961 (((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-nap...) Show SMILES CCCN(CCC)[C@@H]1CCc2c(OC)cccc2[C@@H]1C Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Göteborg Curated by ChEMBL					Assay Description Evaluated for binding towards Dopamine receptor D2 using [3H]-N-0437 as radioligand from rat striatal membrane				J Med Chem 36: 3188-96 (1993) BindingDB Entry DOI: 10.7270/Q2VH5MWJ
University of Göteborg Curated by ChEMBL					More data for this Ligand-Target Pair