Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50044235![]() (CHEMBL292274 | Dimethyl-(S)-6,7,8,9-tetrahydro-3H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 377 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Upjohn Laboratories Curated by ChEMBL | Assay Description Binding affinity rat Dopamine receptor D2 expressed in CHO-K1 cells by [3H]U-86170 displacement. | J Med Chem 38: 2217-30 (1995) BindingDB Entry DOI: 10.7270/Q28G8MBW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50044235![]() (CHEMBL292274 | Dimethyl-(S)-6,7,8,9-tetrahydro-3H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.58E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Göteborg Curated by ChEMBL | Assay Description Displacement of [3H]-spiperone from dopamine receptor D2 | J Med Chem 36: 2059-65 (1993) BindingDB Entry DOI: 10.7270/Q2MP52CR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50044235![]() (CHEMBL292274 | Dimethyl-(S)-6,7,8,9-tetrahydro-3H-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 9.51E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of G£teborg Curated by ChEMBL | Assay Description In vitro binding activity against dopamine receptor D2 from homogenized rat brain, using [3H]spiperone as the radioligand. | J Med Chem 32: 2273-6 (1989) BindingDB Entry DOI: 10.7270/Q2KD1ZG8 | |||||||||||
More data for this Ligand-Target Pair |