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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50048811'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50048811
PNG
(2-[(Z)-4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl...)
Show SMILES O=C1N(C\C=C/CN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12
Show InChI InChI=1S/C23H22N4O2S/c28-22-17-7-1-2-8-18(17)23(29)27(22)12-6-5-11-25-13-15-26(16-14-25)21-19-9-3-4-10-20(19)30-24-21/h1-10H,11-16H2/b6-5-
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Similars
Article
PubMed
n/an/a 130n/an/an/an/an/an/a



Glaxo Wellcome Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-raclopride binding at Dopamine receptor D2 from rat striata.

J Med Chem 39: 149-57 (1996)


Article DOI: 10.1021/jm9502201
BindingDB Entry DOI: 10.7270/Q2TQ60MN
More data for this
Ligand-Target Pair