Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50198272 (1-((1H-indol-3-yl)methyl)-4-(2,3-dichlorophenyl)pi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 26.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Displacement of [125I]IABN from human dopamine D2L receptor expressed in HEK293 cells | Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50198272 (1-((1H-indol-3-yl)methyl)-4-(2,3-dichlorophenyl)pi...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 34.3 | n/a | n/a | n/a | n/a |
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL | Assay Description Antagonist activity at human dopamine D2 receptor expressed in CHO cells assessed as inhibition of quinpirole stimulated mitogenesis | Bioorg Med Chem Lett 17: 745-9 (2007) Article DOI: 10.1016/j.bmcl.2006.10.076 BindingDB Entry DOI: 10.7270/Q2N879FG | |||||||||||
More data for this Ligand-Target Pair |