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Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50421912'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Rattus norvegicus (rat))		BDBM50421912
PNG
(CHEMBL545447)
Show SMILES [O-][N+](=O)c1ccc(CCN2CC[C@@H]3[C@@H](CCc4ccccc34)C2)cc1 |r|
Show InChI InChI=1S/C21H24N2O2/c24-23(25)19-9-5-16(6-10-19)11-13-22-14-12-21-18(15-22)8-7-17-3-1-2-4-20(17)21/h1-6,9-10,18,21H,7-8,11-15H2/t18-,21+/m0/s1
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PubMed
n/an/a 589n/an/an/an/an/an/a



Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL


Assay Description
Inhibition of [3H](-)-sulpiride binding to rat striatum dopamine receptor D2

J Med Chem 35: 2025-33 (1992)


BindingDB Entry DOI: 10.7270/Q2MP54K8
More data for this
Ligand-Target Pair