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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50533617'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50533617
PNG
(CHEMBL4555307)
Show SMILES CCc1cccc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)c1Cl
Show InChI InChI=1S/C24H30ClN5O/c1-2-19-8-7-9-21(23(19)25)29-16-14-28(15-17-29)12-6-4-11-26-24(31)20-18-30-13-5-3-10-22(30)27-20/h3,5,7-10,13,18H,2,4,6,11-12,14-17H2,1H3,(H,26,31)
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Article
PubMed
 5.60n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ...

J Med Chem 59: 7634-50 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00860
BindingDB Entry DOI: 10.7270/Q2NS0ZDD
More data for this
Ligand-Target Pair