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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(2) dopamine receptor' and Ligand = 'BDBM50533620'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(2) dopamine receptor


(Homo sapiens (Human))		BDBM50533620
PNG
(CHEMBL4476699)
Show SMILES CCc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4o3)CC2)c1Cl
Show InChI InChI=1S/C25H30ClN3O2/c1-2-19-9-7-10-21(24(19)26)29-16-14-28(15-17-29)13-6-5-12-27-25(30)23-18-20-8-3-4-11-22(20)31-23/h3-4,7-11,18H,2,5-6,12-17H2,1H3,(H,27,30)
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Article
PubMed
 6.30n/an/an/an/an/an/an/an/a



National Institute on Drug Abuse-Intramural Research Program

Curated by ChEMBL


Assay Description
Displacement of [3H]N-methylspiperone from human dopamine D2L receptor expressed in HEK293 cell membranes incubated for 1 hr by liquid scintillation ...

J Med Chem 59: 7634-50 (2016)


Article DOI: 10.1021/acs.jmedchem.6b00860
BindingDB Entry DOI: 10.7270/Q2NS0ZDD
More data for this
Ligand-Target Pair