BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50020680'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia & Upjohn Curated by ChEMBL					Assay Description Binding affinity towards Dopamine receptor D3 by displacement of [3H]-(+)-7-OH-DPAT.				J Med Chem 40: 639-46 (1997) Article DOI: 10.1021/jm960360q BindingDB Entry DOI: 10.7270/Q29P30R9
Pharmacia & Upjohn Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	29.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat D3 receptor expressed in HEK293 cells				Bioorg Med Chem 18: 5661-74 (2010) Article DOI: 10.1016/j.bmc.2010.06.025 BindingDB Entry DOI: 10.7270/Q2W37WJ9
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	36.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Displacement of [3H]spiperone form human cloned dopamine D3 receptor expressed in CHO cells				Bioorg Med Chem Lett 19: 2133-8 (2009) Article DOI: 10.1016/j.bmcl.2009.03.015 BindingDB Entry DOI: 10.7270/Q28W3FH9
Institut de Recherches Servier Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP K_i Database									J Pharmacol Exp Ther 309: 903-20 (2004) Article DOI: 10.1124/jpet.103.062398 BindingDB Entry DOI: 10.7270/Q29S1PM2
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	37.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by PDSP K_i Database									J Pharmacol Exp Ther 303: 791-804 (2002) Article DOI: 10.1124/jpet.102.039867 BindingDB Entry DOI: 10.7270/Q2MG7N2F
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]nemonapride from Rattus norvegicus (rat) wild type dopamine D3 receptor transfected in african green monkey COS7 cells after 1 hr...				Citation and Details Article DOI: 10.1007/s00044-004-0006-x BindingDB Entry DOI: 10.7270/Q2377CM7
TBA					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against constrictor response to electrical stimulation in the isolated perfused rabbit ear artery(REA) expressing dopamine recept...				J Med Chem 28: 1533-6 (1985) BindingDB Entry DOI: 10.7270/Q2CC12WP
TBA Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10.3	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Agonist activity at human dopamine D3 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding				Bioorg Med Chem 18: 5661-74 (2010) Article DOI: 10.1016/j.bmc.2010.06.025 BindingDB Entry DOI: 10.7270/Q2W37WJ9
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	19.2	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Agonist activity at human dopamine D3 receptor expressed in mouse AtT-20 cells assessed as stimulation of [35S]GTPgamma binding				J Med Chem 53: 1023-37 (2010) Article DOI: 10.1021/jm901184n BindingDB Entry DOI: 10.7270/Q29023VM
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant dopamine D3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation				Bioorg Med Chem Lett 17: 6691-6 (2007) Article DOI: 10.1016/j.bmcl.2007.10.059 BindingDB Entry DOI: 10.7270/Q23J3CQ5
Pfizer Global Research & Development Curated by ChEMBL					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50020680 (4-[2-(dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-...) Show SMILES CCCN(CCC)CCc1cccc2NC(=O)Cc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	10.3	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Agonist activity at human dopamine D3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay				J Med Chem 53: 2114-25 (2010) Article DOI: 10.1021/jm901618d BindingDB Entry DOI: 10.7270/Q20K28QZ
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair