Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50154842'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154842 (CHEMBL3775589 | US10273244, Example 12 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2)n1C Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aptuit s.r.l Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation counter metho...				Bioorg Med Chem 24: 1619-36 (2016) Article DOI: 10.1016/j.bmc.2016.02.031 BindingDB Entry DOI: 10.7270/Q29P33JV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154842 (CHEMBL3775589 | US10273244, Example 12 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2)n1C Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aptuit s.r.l Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation counter metho...				Bioorg Med Chem 24: 1619-36 (2016) Article DOI: 10.1016/j.bmc.2016.02.031 BindingDB Entry DOI: 10.7270/Q29P33JV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154842 (CHEMBL3775589 | US10273244, Example 12 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2)n1C Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aptuit s.r.l Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by [35S]GTP-gamma-S binding assay in presence of 3...				Bioorg Med Chem 24: 1619-36 (2016) Article DOI: 10.1016/j.bmc.2016.02.031 BindingDB Entry DOI: 10.7270/Q29P33JV
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154842 (CHEMBL3775589 | US10273244, Example 12 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2)n1C Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	4.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INDIVIOR UK LIMITED US Patent					Assay Description [3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD...				US Patent US10584135 (2020) BindingDB Entry DOI: 10.7270/Q29S1TFG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154842 (CHEMBL3775589 | US10273244, Example 12 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2)n1C Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	4.17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IRBM/Merck					Assay Description 3H]-Spiperone Binding Assay at hD3 and hD4 recombinant receptors CHO cells transiently transfected with human dopamine type 3 or 4 receptors (CHO-hD3...				Bioorg Med Chem Lett 18: 3456-61 (2008) BindingDB Entry DOI: 10.7270/Q2RN3B5H
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50154842 (CHEMBL3775589 | US10273244, Example 12 | US1058413...) Show SMILES Cc1ncoc1-c1nnc(SCCCN2CC3CCN(C3C2)c2ccccc2)n1C Show InChI InChI=1S/C22H28N6OS/c1-16-20(29-15-23-16)21-24-25-22(26(21)2)30-12-6-10-27-13-17-9-11-28(19(17)14-27)18-7-4-3-5-8-18/h3-5,7-8,15,17,19H,6,9-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aptuit s.r.l Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation counter metho...				Bioorg Med Chem 24: 1619-36 (2016) Article DOI: 10.1016/j.bmc.2016.02.031 BindingDB Entry DOI: 10.7270/Q29P33JV
					More data for this Ligand-Target Pair