Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(3) dopamine receptor' and Ligand = 'BDBM50192024'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50192024 (CHEMBL3941520 | US10239870, Example 187) Show SMILES Cc1nc(ccc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)n1C)C(N)=O |r| Show InChI InChI=1S/C26H29F3N6OS/c1-16-19(8-9-21(31-16)22(30)36)23-32-33-24(34(23)2)37-13-3-11-35-12-10-25(15-35)14-20(25)17-4-6-18(7-5-17)26(27,28)29/h4-9,20H,3,10-15H2,1-2H3,(H2,30,36)/t20-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aptuit s.r.l. Curated by ChEMBL					Assay Description Antagonist activity at human dopamine D3 receptor expressed in CHO cell membranes after 90 mins in presence of quinelorane by [35S]-GTPgammaS binding...				J Med Chem 59: 8549-76 (2016) Article DOI: 10.1021/acs.jmedchem.6b00972 BindingDB Entry DOI: 10.7270/Q2SQ9298
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50192024 (CHEMBL3941520 | US10239870, Example 187) Show SMILES Cc1nc(ccc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)n1C)C(N)=O |r| Show InChI InChI=1S/C26H29F3N6OS/c1-16-19(8-9-21(31-16)22(30)36)23-32-33-24(34(23)2)37-13-3-11-35-12-10-25(15-35)14-20(25)17-4-6-18(7-5-17)26(27,28)29/h4-9,20H,3,10-15H2,1-2H3,(H2,30,36)/t20-,25+/m1/s1	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	1.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology					Assay Description [125I]-7OH-PIPAT Binding Assay at rat native D3 receptor on membranes from rat ventral striatum. Homogenates from frozen rat brain ventral striatum (...				J Med Chem 51: 2816-32 (2008) BindingDB Entry DOI: 10.7270/Q2HT2RNX
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50192024 (CHEMBL3941520 | US10239870, Example 187) Show SMILES Cc1nc(ccc1-c1nnc(SCCCN2CC[C@]3(C[C@@H]3c3ccc(cc3)C(F)(F)F)C2)n1C)C(N)=O |r| Show InChI InChI=1S/C26H29F3N6OS/c1-16-19(8-9-21(31-16)22(30)36)23-32-33-24(34(23)2)37-13-3-11-35-12-10-25(15-35)14-20(25)17-4-6-18(7-5-17)26(27,28)29/h4-9,20H,3,10-15H2,1-2H3,(H2,30,36)/t20-,25+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Aptuit s.r.l. Curated by ChEMBL					Assay Description Displacement of [3H]-spiperone from human dopamine D3 receptor expressed in CHO-K1 cell membranes after 90 mins by liquid scintillation counting				J Med Chem 59: 8549-76 (2016) Article DOI: 10.1021/acs.jmedchem.6b00972 BindingDB Entry DOI: 10.7270/Q2SQ9298
					More data for this Ligand-Target Pair