Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM466535![]() (4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent | Assay Description The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b... | US Patent US11014905 (2021) BindingDB Entry DOI: 10.7270/Q2C53PZQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM466535![]() (4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | 11 | n/a | n/a | n/a | n/a | n/a | n/a |
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent | Assay Description The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b... | US Patent US10800755 (2020) BindingDB Entry DOI: 10.7270/Q2TM7F5J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(4) dopamine receptor (Homo sapiens (Human)) | BDBM466535![]() (4,4-Difluoro-N-(2-{4-[6-(trifluoromethyl)pyridin-2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | US Patent | n/a | n/a | n/a | n/a | 11.9 | n/a | n/a | n/a | n/a |
SUMITOMO DAINIPPON PHARMA CO., LTD. US Patent | Assay Description Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ... | US Patent US10800755 (2020) BindingDB Entry DOI: 10.7270/Q2TM7F5J | |||||||||||
More data for this Ligand-Target Pair |