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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50505721'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
D(4) dopamine receptor


(Homo sapiens (Human))		BDBM50505721
PNG
(CHEMBL4437233)
Show SMILES COc1ccccc1N1CCN(CCCNC(=O)NN(Cc2cccc(F)c2)c2ccc(F)cc2)CC1
Show InChI InChI=1S/C28H33F2N5O2/c1-37-27-9-3-2-8-26(27)34-18-16-33(17-19-34)15-5-14-31-28(36)32-35(25-12-10-23(29)11-13-25)21-22-6-4-7-24(30)20-22/h2-4,6-13,20H,5,14-19,21H2,1H3,(H2,31,32,36)
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PC cid
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Article
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 3.80n/an/an/an/an/an/an/an/a



Friedrich-Alexander-Universit£t Erlangen-N£rnberg

Curated by ChEMBL


Assay Description
Displacement of [3H] Spiperone from human D4.4 receptor expressed in CHO cells by competitive radioligand binding assay

J Med Chem 62: 9658-9679 (2019)


Article DOI: 10.1021/acs.jmedchem.9b01085
BindingDB Entry DOI: 10.7270/Q2GB27BJ
More data for this
Ligand-Target Pair