Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50523478'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523478 (CHEMBL4473792) Show SMILES Cc1ccc(cc1)C1CCN(CC(=O)Nc2cccc(C)c2)CC1 Show InChI InChI=1S/C21H26N2O/c1-16-6-8-18(9-7-16)19-10-12-23(13-11-19)15-21(24)22-20-5-3-4-17(2)14-20/h3-9,14,19H,10-13,15H2,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523478 (CHEMBL4473792) Show SMILES Cc1ccc(cc1)C1CCN(CC(=O)Nc2cccc(C)c2)CC1 Show InChI InChI=1S/C21H26N2O/c1-16-6-8-18(9-7-16)19-10-12-23(13-11-19)15-21(24)22-20-5-3-4-17(2)14-20/h3-9,14,19H,10-13,15H2,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523478 (CHEMBL4473792) Show SMILES Cc1ccc(cc1)C1CCN(CC(=O)Nc2cccc(C)c2)CC1 Show InChI InChI=1S/C21H26N2O/c1-16-6-8-18(9-7-16)19-10-12-23(13-11-19)15-21(24)22-20-5-3-4-17(2)14-20/h3-9,14,19H,10-13,15H2,1-2H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair