Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'D(4) dopamine receptor' and Ligand = 'BDBM50523486'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523486 (CHEMBL4437912) Show SMILES CCc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1 Show InChI InChI=1S/C20H25N3O/c1-2-16-6-5-7-18(14-16)22-20(24)15-23-12-9-17(10-13-23)19-8-3-4-11-21-19/h3-8,11,14,17H,2,9-10,12-13,15H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	82	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Displacement of [3H]N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by scintillation counting me...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523486 (CHEMBL4437912) Show SMILES CCc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1 Show InChI InChI=1S/C20H25N3O/c1-2-16-6-5-7-18(14-16)22-20(24)15-23-12-9-17(10-13-23)19-8-3-4-11-21-19/h3-8,11,14,17H,2,9-10,12-13,15H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as suppression of dopamine-induced inhibition of forskolin-stimulated cAMP...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523486 (CHEMBL4437912) Show SMILES CCc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1 Show InChI InChI=1S/C20H25N3O/c1-2-16-6-5-7-18(14-16)22-20(24)15-23-12-9-17(10-13-23)19-8-3-4-11-21-19/h3-8,11,14,17H,2,9-10,12-13,15H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Antagonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of dopamine-induced beta-arrestin recruitment measured after...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50523486 (CHEMBL4437912) Show SMILES CCc1cccc(NC(=O)CN2CCC(CC2)c2ccccn2)c1 Show InChI InChI=1S/C20H25N3O/c1-2-16-6-5-7-18(14-16)22-20(24)15-23-12-9-17(10-13-23)19-8-3-4-11-21-19/h3-8,11,14,17H,2,9-10,12-13,15H2,1H3,(H,22,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	539	n/a	n/a	n/a	n/a
Rowan University Curated by ChEMBL					Assay Description Agonist activity at human D4 receptor expressed in CHOK1 cells assessed as inhibition of forskolin-induced cAMP accumulation measured after 30 mins b...				J Med Chem 62: 3722-3740 (2019) Article DOI: 10.1021/acs.jmedchem.9b00231 BindingDB Entry DOI: 10.7270/Q20C505J
					More data for this Ligand-Target Pair