Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DCN1-like protein 1/NEDD8-conjugating enzyme Ubc12' and Ligand = 'BDBM50245142'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DCN1-like protein 1/NEDD8-conjugating enzyme Ubc12 (Homo sapiens)	BDBM50245142 (CHEMBL4105639 | US11116757, No. A47) Show SMILES CCCC(C)N1CCC(CC1)N(Cc1ccccc1)C(=O)Nc1ccc(C#N)c(c1)C(F)(F)F Show InChI InChI=1S/C26H31F3N4O/c1-3-7-19(2)32-14-12-23(13-15-32)33(18-20-8-5-4-6-9-20)25(34)31-22-11-10-21(17-30)24(16-22)26(27,28)29/h4-6,8-11,16,19,23H,3,7,12-15,18H2,1-2H3,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	259	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The TR-FRET assay is illustrated in FIG. 3A and FIG. 3B. The TR-FRET assay cocktail was prepared by mixing 50 nM Biotin-DCN1P, 20 nM AlexaFluor488 UB...				Citation and Details BindingDB Entry DOI: 10.7270/Q2736V2B
					More data for this Ligand-Target Pair