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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'DCN1-like protein 5' and Ligand = 'BDBM50525313'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DCN1-like protein 5


(Homo sapiens)		BDBM50525313
PNG
(CHEMBL4592844)
Show SMILES Cc1ccc(cc1)-c1nc(SCC#C)nc(Sc2nccs2)c1C#N
Show InChI InChI=1S/C18H12N4S3/c1-3-9-23-17-21-15(13-6-4-12(2)5-7-13)14(11-19)16(22-17)25-18-20-8-10-24-18/h1,4-8,10H,9H2,2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2.10n/an/an/an/an/an/an/an/a



Zhengzhou University

Curated by ChEMBL


Assay Description
Binding affinity to N-terminal GST tagged recombinant DCN5 (unknown origin) (47 to 237 residues) expressed in Escherichia coli BL21(DE3) assessed as ...

J Med Chem 62: 5382-5403 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00003
BindingDB Entry DOI: 10.7270/Q2GT5RM9
More data for this
Ligand-Target Pair
DCN1-like protein 5


(Homo sapiens)		BDBM50525313
PNG
(CHEMBL4592844)
Show SMILES Cc1ccc(cc1)-c1nc(SCC#C)nc(Sc2nccs2)c1C#N
Show InChI InChI=1S/C18H12N4S3/c1-3-9-23-17-21-15(13-6-4-12(2)5-7-13)14(11-19)16(22-17)25-18-20-8-10-24-18/h1,4-8,10H,9H2,2H3
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 2.14E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to DCN5 (unknown origin) assessed as inhibitory constant

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01207
BindingDB Entry DOI: 10.7270/Q2JD51NJ
More data for this
Ligand-Target Pair