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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA (cytosine-5)-methyltransferase 3B' and Ligand = 'BDBM50538697'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA (cytosine-5)-methyltransferase 3B


(Homo sapiens (Human))
BDBM50538697
PNG
(CHEMBL4641323)
Show SMILES Cc1nccc(n1)-c1cccc(NS(=O)(=O)c2cc(cc(C)c2C)C(O)=O)c1
Show InChI InChI=1S/C20H19N3O4S/c1-12-9-16(20(24)25)11-19(13(12)2)28(26,27)23-17-6-4-5-15(10-17)18-7-8-21-14(3)22-18/h4-11,23H,1-3H3,(H,24,25)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.04E+4n/an/an/an/an/an/a



Yale University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant DNMT3B expressed in baculovirus infected insect cells using CpG site containing internally quenched hairpin oligonucl...


ACS Med Chem Lett 11: 971-976 (2020)


Article DOI: 10.1021/acsmedchemlett.0c00011
BindingDB Entry DOI: 10.7270/Q2H998QH
More data for this
Ligand-Target Pair