Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A/B' and Ligand = 'BDBM159897'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM159897 (BDBM159898 | US9040528, 53) Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)-n2cncn2)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H18FN7O5/c1-8-5-27-13-10(3-11-14(12(13)21)33-26-16(11)28-7-22-6-23-28)4-20(15(27)9(2)32-8)17(29)24-19(31)25-18(20)30/h3,6-9,15H,4-5H2,1-2H3,(H2,24,25,29,30,31)/t8-,9+,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/ml of topologic...				US Patent US9040528 (2015) BindingDB Entry DOI: 10.7270/Q2PG1QG0
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Staphylococcus aureus)	BDBM159897 (BDBM159898 | US9040528, 53) Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)-n2cncn2)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H18FN7O5/c1-8-5-27-13-10(3-11-14(12(13)21)33-26-16(11)28-7-22-6-23-28)4-20(15(27)9(2)32-8)17(29)24-19(31)25-18(20)30/h3,6-9,15H,4-5H2,1-2H3,(H2,24,25,29,30,31)/t8-,9+,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00266 BindingDB Entry DOI: 10.7270/Q2C251HR
					More data for this Ligand-Target Pair
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM159897 (BDBM159898 | US9040528, 53) Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)-n2cncn2)C(=O)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H18FN7O5/c1-8-5-27-13-10(3-11-14(12(13)21)33-26-16(11)28-7-22-6-23-28)4-20(15(27)9(2)32-8)17(29)24-19(31)25-18(20)30/h3,6-9,15H,4-5H2,1-2H3,(H2,24,25,29,30,31)/t8-,9+,15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/ml of topologic...				US Patent US9040528 (2015) BindingDB Entry DOI: 10.7270/Q2PG1QG0
					More data for this Ligand-Target Pair