Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA gyrase subunit A' and Ligand = 'BDBM139410'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A (Escherichia coli (strain K12))	BDBM139410 (US8889671, 40) Show SMILES C[C@@H]1CN2[C@H]([C@H](C)O1)C1(Cc3cc4c(noc4c(F)c23)N2C[C@@H](OC2=O)C=NO)C(=O)NC(=O)NC1=O |r,w:27.32| Show InChI InChI=1S/C22H21FN6O8/c1-8-6-28-14-10(4-22(16(28)9(2)35-8)18(30)25-20(32)26-19(22)31)3-12-15(13(14)23)37-27-17(12)29-7-11(5-24-34)36-21(29)33/h3,5,8-9,11,16,34H,4,6-7H2,1-2H3,(H2,25,26,30,31,32)/t8-,9+,11+,16-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	380	n/a	n/a	n/a	n/a	7.5	n/a
AstraZeneca AB US Patent					Assay Description In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...				US Patent US8889671 (2014) BindingDB Entry DOI: 10.7270/Q22J69JX
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