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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase III PolC-type' and Ligand = 'BDBM50176079'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA polymerase III PolC-type


(Bacillus subtilis)		BDBM50176079
PNG
(3-[2-(4-Benzoyl-piperazin-1-yl)-ethyl]-6-(3-ethyl-...)
Show SMILES CCc1cc(Nc2cc(=O)n(CCN3CCN(CC3)C(=O)c3ccccc3)c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C26H31N5O3/c1-3-20-17-22(10-9-19(20)2)27-23-18-24(32)31(26(34)28-23)16-13-29-11-14-30(15-12-29)25(33)21-7-5-4-6-8-21/h4-10,17-18,27H,3,11-16H2,1-2H3,(H,28,34)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents
Article
PubMed
 77n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)

J Med Chem 48: 7063-74 (2005)


Article DOI: 10.1021/jm050517r
BindingDB Entry DOI: 10.7270/Q2W66MJN
More data for this
Ligand-Target Pair