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Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA polymerase III PolC-type' and Ligand = 'BDBM50176082'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
DNA polymerase III PolC-type


(Bacillus subtilis)
BDBM50176082
PNG
(6-(3-Ethyl-4-methyl-phenylamino)-3-(2-oxo-propyl)-...)
Show SMILES CCc1cc(Nc2cc(=O)n(CC(C)=O)c(=O)[nH]2)ccc1C
Show InChI InChI=1S/C16H19N3O3/c1-4-12-7-13(6-5-10(12)2)17-14-8-15(21)19(9-11(3)20)16(22)18-14/h5-8,17H,4,9H2,1-3H3,(H,18,22)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
300n/an/an/an/an/an/an/an/a



GLSynthesis Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against Bacillus subtilis DNA polymerase IIIC using [3H]dTMP 250 pM (30 degree C for 10 min)


J Med Chem 48: 7063-74 (2005)


Article DOI: 10.1021/jm050517r
BindingDB Entry DOI: 10.7270/Q2W66MJN
More data for this
Ligand-Target Pair