Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2 (Drosophila melanogaster) | BDBM50081428 ((4R,4aS)-4,8-Dihydroxy-6-methyl-9-oxo-4,9-dihydro-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Ajinomoto Co., Inc. Curated by ChEMBL | Assay Description In vitro inhibitory activity against topoisomerase II (Topo II) by using decatenation assay | Bioorg Med Chem Lett 9: 2653-6 (1999) BindingDB Entry DOI: 10.7270/Q2X34XZ8 | |||||||||||
More data for this Ligand-Target Pair |