Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha/2-beta' and Ligand = 'BDBM50471909'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50471909 (CHEMBL433875) Show SMILES [H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(O)c(OC)c1)c1cc3OCOc3cc1[C@H]2OC1CC(C2OC(C)OCC2O1)N(C)C Show InChI InChI=1S/C31H37NO11/c1-14-37-12-24-30(41-14)19(32(2)3)10-25(42-24)43-29-17-9-21-20(39-13-40-21)8-16(17)26(27-18(29)11-38-31(27)34)15-6-22(35-4)28(33)23(7-15)36-5/h6-9,14,18-19,24-27,29-30,33H,10-13H2,1-5H3/t14?,18-,19?,24?,25?,26+,27-,29+,30?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
UMR 176 CNRS/Institut Curie Curated by ChEMBL					Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II				J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB
					More data for this Ligand-Target Pair
DNA topoisomerase 2-alpha/2-beta (Homo sapiens (Human))	BDBM50471909 (CHEMBL433875) Show SMILES [H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(O)c(OC)c1)c1cc3OCOc3cc1[C@H]2OC1CC(C2OC(C)OCC2O1)N(C)C Show InChI InChI=1S/C31H37NO11/c1-14-37-12-24-30(41-14)19(32(2)3)10-25(42-24)43-29-17-9-21-20(39-13-40-21)8-16(17)26(27-18(29)11-38-31(27)34)15-6-22(35-4)28(33)23(7-15)36-5/h6-9,14,18-19,24-27,29-30,33H,10-13H2,1-5H3/t14?,18-,19?,24?,25?,26+,27-,29+,30?/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
UMR 176 CNRS/Institut Curie Curated by ChEMBL					Assay Description Concentration of compound at which inhibitory activity detected against DNA topoisomerase II				J Med Chem 41: 4475-85 (1998) Article DOI: 10.1021/jm9800752 BindingDB Entry DOI: 10.7270/Q2251MZB
					More data for this Ligand-Target Pair