Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA topoisomerase 2-beta (Homo sapiens (Human)) | BDBM22984![]() ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 727 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of Topoisomerase II beta (unknown origin) relative to control | Citation and Details Article DOI: 10.1016/j.bmc.2020.115674 BindingDB Entry DOI: 10.7270/Q2TM7FQQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-beta (Homo sapiens (Human)) | BDBM22984![]() ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cairo University Curated by ChEMBL | Assay Description Inhibition of human topoisomerase 2beta after 2 hrs at 37 degC by ELISA | Eur J Med Chem 143: 1807-1825 (2018) Article DOI: 10.1016/j.ejmech.2017.10.075 BindingDB Entry DOI: 10.7270/Q2BC426J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
DNA topoisomerase 2-beta (Homo sapiens (Human)) | BDBM22984![]() ((8S,10S)-10-{[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-me...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Cairo University Curated by ChEMBL | Assay Description Inhibition of human topoisomerase-2B after 2 hrs by ELISA | Eur J Med Chem 150: 403-418 (2018) Article DOI: 10.1016/j.ejmech.2018.03.026 BindingDB Entry DOI: 10.7270/Q2MS3WCZ | |||||||||||
More data for this Ligand-Target Pair |