Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-beta' and Ligand = 'BDBM50473498'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-beta (Homo sapiens (Human))	BDBM50473498 (CHEMBL157831 | Ro-616653) Show SMILES COC(=O)c1c(Br)c(OC)cc(O)c1CSC[C@H](Nc1nc(cs1)-c1ccc(cc1)[N+]([O-])=O)c1nc(C)no1 |r| Show InChI InChI=1S/C24H22BrN5O7S2/c1-12-26-22(37-29-12)17(28-24-27-16(11-39-24)13-4-6-14(7-5-13)30(33)34)10-38-9-15-18(31)8-19(35-2)21(25)20(15)23(32)36-3/h4-8,11,17,31H,9-10H2,1-3H3,(H,27,28)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antibacterial activity against Escherichia coli DNA gyrase				J Med Chem 44: 619-26 (2001) Article DOI: 10.1021/jm0010623 BindingDB Entry DOI: 10.7270/Q2T43WT3
					More data for this Ligand-Target Pair
DNA topoisomerase 2-beta (Homo sapiens (Human))	BDBM50473498 (CHEMBL157831 | Ro-616653) Show SMILES COC(=O)c1c(Br)c(OC)cc(O)c1CSC[C@H](Nc1nc(cs1)-c1ccc(cc1)[N+]([O-])=O)c1nc(C)no1 |r| Show InChI InChI=1S/C24H22BrN5O7S2/c1-12-26-22(37-29-12)17(28-24-27-16(11-39-24)13-4-6-14(7-5-13)30(33)34)10-38-9-15-18(31)8-19(35-2)21(25)20(15)23(32)36-3/h4-8,11,17,31H,9-10H2,1-3H3,(H,27,28)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
Bayer AG Curated by ChEMBL					Assay Description Antibacterial activity against Micrococcus luteus DNA gyrase.				J Med Chem 44: 619-26 (2001) Article DOI: 10.1021/jm0010623 BindingDB Entry DOI: 10.7270/Q2T43WT3
					More data for this Ligand-Target Pair