Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-(apurinic or apyrimidinic site) endonuclease (Homo sapiens (Human)) | BDBM26621 (4-[dihydroxy(oxo)--stibanyl]-2-nitrobenzoic acid |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents | Article PubMed | 19 | -43.6 | 4 | n/a | n/a | n/a | n/a | 7.5 | 22 |
The Johns Hopkins University | Assay Description The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w... | Mol Pharmacol 73: 669-77 (2008) Article DOI: 10.1124/mol.107.042622 BindingDB Entry DOI: 10.7270/Q2WS8RJX | |||||||||||
More data for this Ligand-Target Pair |