Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' and Ligand = 'BDBM128745'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM128745 (US8802712, 3) Show SMILES COc1cc2ncc3n(C)nc(-c4ccc(C#N)c(Br)c4)c3c2cc1OC Show InChI InChI=1S/C20H15BrN4O2/c1-25-16-10-23-15-8-18(27-3)17(26-2)7-13(15)19(16)20(24-25)11-4-5-12(9-22)14(21)6-11/h4-8,10H,1-3H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US8802712 (2014) BindingDB Entry DOI: 10.7270/Q2VM49ZC
					More data for this Ligand-Target Pair