Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' and Ligand = 'BDBM128770'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM128770 (US8802712, 28) Show SMILES COc1cc2ncc3n(C)nc(-c4ccc(cc4)C#N)c3c2cc1OCc1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C31H29N5O3/c1-35-27-18-33-26-16-28(37-2)29(15-25(26)30(27)31(34-35)24-8-6-21(17-32)7-9-24)39-20-23-5-3-4-22(14-23)19-36-10-12-38-13-11-36/h3-9,14-16,18H,10-13,19-20H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.300	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US8802712 (2014) BindingDB Entry DOI: 10.7270/Q2VM49ZC
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