Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'DNA-dependent protein kinase catalytic subunit' and Ligand = 'BDBM179333'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA-dependent protein kinase catalytic subunit (Homo sapiens (Human))	BDBM179333 (US9126952, 36) Show SMILES Clc1nc(N2CCCC(Cc3nccs3)C2)c2ccc(cc2n1)N1CCOCC1 Show InChI InChI=1S/C21H24ClN5OS/c22-21-24-18-13-16(26-7-9-28-10-8-26)3-4-17(18)20(25-21)27-6-1-2-15(14-27)12-19-23-5-11-29-19/h3-5,11,13,15H,1-2,6-10,12,14H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.4	25
Merck Patent GmbH US Patent					Assay Description The kinase assay was carried out in streptavidin-coated 348-well microtitre FlashPlates®. To this end, 1.5 μg of the DNA-PK/protein complex and ...				US Patent US9126952 (2015) BindingDB Entry DOI: 10.7270/Q2JH3JZ2
					More data for this Ligand-Target Pair