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Found 1 hit Enz. Inhib. hit(s) with Target = 'Delta-type opioid receptor' and Ligand = 'BDBM50257686'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Delta-type opioid receptor


(Homo sapiens (Human))		BDBM50257686
PNG
(CHEMBL522317 | N-(1-(4-aminopyridin-2-yl)-4-phenyl...)
Show SMILES Nc1ccnc(c1)N1CCC(CC1)(NC(=O)c1ccccn1)c1ccccc1
Show InChI InChI=1S/C22H23N5O/c23-18-9-13-25-20(16-18)27-14-10-22(11-15-27,17-6-2-1-3-7-17)26-21(28)19-8-4-5-12-24-19/h1-9,12-13,16H,10-11,14-15H2,(H2,23,25)(H,26,28)
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PC cid
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Article
PubMed
n/an/an/an/a 60n/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Agonist activity at delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production by ALPHAscreen assay

Bioorg Med Chem Lett 19: 1702-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.01.106
BindingDB Entry DOI: 10.7270/Q21G0M40
More data for this
Ligand-Target Pair