Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM411430'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM411430 (US10385066, Example 2) Show SMILES FC(F)(F)Oc1cccc(c1)-n1ccc2cc(ccc12)N1CCOc2ncnc(Cl)c2C1=O Show InChI InChI=1S/C22H14ClF3N4O3/c23-19-18-20(28-12-27-19)32-9-8-30(21(18)31)15-4-5-17-13(10-15)6-7-29(17)14-2-1-3-16(11-14)33-22(24,25)26/h1-7,10-12H,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline LLC US Patent					Assay Description LE assay: For inhibition of triacylglycerol product formation, 11 uL, reactions were nm in white Polyplate-384 (PerkinElmer6007300) starting with a 3...				US Patent US10385066 (2019) BindingDB Entry DOI: 10.7270/Q2WD42X8
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