Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50003718'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50003718 (CHEMBL3235284) Show SMILES CN(C)c1nc(N)c2N=C(COc2n1)c1ccc(Br)cc1 |c:8| Show InChI InChI=1S/C14H14BrN5O/c1-20(2)14-18-12(16)11-13(19-14)21-7-10(17-11)8-3-5-9(15)6-4-8/h3-6H,7H2,1-2H3,(H2,16,18,19)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human liver flag-tagged DGAT1 expressed in baculovirus infected insect cells after 2 hrs by SPA				J Med Chem 57: 3464-83 (2014) Article DOI: 10.1021/jm500135c BindingDB Entry DOI: 10.7270/Q23X886W
					More data for this Ligand-Target Pair