Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50005650'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50005650 (CHEMBL3235426) Show SMILES COc1ccccc1NC(=O)Nc1ccc(cc1)-c1cnc(s1)C(=O)N[C@H]1CC[C@@H](CC1)C(O)=O |r,wU:26.28,wD:29.35,(1.32,-43.95,;2.65,-43.18,;2.64,-41.64,;1.31,-40.88,;1.31,-39.33,;2.64,-38.56,;3.97,-39.33,;3.96,-40.87,;5.3,-41.64,;6.63,-40.87,;6.63,-39.33,;7.96,-41.64,;9.3,-40.88,;9.3,-39.33,;10.63,-38.56,;11.96,-39.32,;11.97,-40.87,;10.63,-41.65,;13.23,-38.45,;13.28,-36.91,;14.75,-36.47,;15.62,-37.75,;14.68,-38.97,;17.16,-37.79,;17.9,-39.14,;17.97,-36.48,;19.51,-36.52,;20.31,-35.21,;21.85,-35.26,;22.58,-36.61,;21.77,-37.92,;20.23,-37.88,;24.12,-36.66,;24.93,-35.35,;24.85,-38.02,)| Show InChI InChI=1S/C25H26N4O5S/c1-34-20-5-3-2-4-19(20)29-25(33)28-18-10-6-15(7-11-18)21-14-26-23(35-21)22(30)27-17-12-8-16(9-13-17)24(31)32/h2-7,10-11,14,16-17H,8-9,12-13H2,1H3,(H,27,30)(H,31,32)(H2,28,29,33)/t16-,17-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
VIT University Curated by ChEMBL					Assay Description Inhibition of human DGAT1 using 1,2-diacylglycerol/[14C]-oleoyl CoA as substrate assessed as [14C]-triglyceride formation after 10 mins by scintillat...				Eur J Med Chem 79: 203-15 (2014) Article DOI: 10.1016/j.ejmech.2014.03.077 BindingDB Entry DOI: 10.7270/Q23R0VCD
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