Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human)) | BDBM50239480 (CHEMBL4074410) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibition of recombinant human His6-tagged DGAT1 expressed in Sf9 insect cell membranes assessed as inhibition of triglyceride formation using diole... | J Med Chem 60: 4657-4664 (2017) Article DOI: 10.1021/acs.jmedchem.7b00173 BindingDB Entry DOI: 10.7270/Q2B27XF2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse)) | BDBM50239480 (CHEMBL4074410) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
Novartis Institutes for Biomedical Research Curated by ChEMBL | Assay Description Inhibitory activity against purine nucleoside phosphorylase (PNPase ) | J Med Chem 60: 4657-4664 (2017) Article DOI: 10.1021/acs.jmedchem.7b00173 BindingDB Entry DOI: 10.7270/Q2B27XF2 | |||||||||||
More data for this Ligand-Target Pair |