Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50499968'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50499968 (CHEMBL3741457) Show SMILES OC(=O)C[C@H]1CC[C@@H](CC1)c1ccc(cc1)C(=O)Nc1nnc(CCC2CCOC2)s1 |r,wU:7.10,wD:4.3,(-5.61,6,;-6.67,5.39,;-7.74,6,;-6.67,3.85,;-5.34,3.08,;-5.34,1.54,;-4,.77,;-2.67,1.54,;-2.67,3.08,;-4.01,3.85,;-1.33,.77,;,1.54,;1.33,.77,;1.33,-.77,;,-1.54,;-1.33,-.77,;2.67,-1.54,;3.73,-.93,;2.66,-3.08,;4,-3.86,;4.14,-5.38,;5.65,-5.7,;6.42,-4.36,;7.94,-4.2,;8.57,-2.79,;10.1,-2.63,;11.11,-3.77,;12.52,-3.15,;12.36,-1.62,;10.85,-1.3,;5.38,-3.22,)| Show InChI InChI=1S/C23H29N3O4S/c27-21(28)13-15-1-4-17(5-2-15)18-6-8-19(9-7-18)22(29)24-23-26-25-20(31-23)10-3-16-11-12-30-14-16/h6-9,15-17H,1-5,10-14H2,(H,27,28)(H,24,26,29)/t15-,16?,17-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	233	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi-aventis R&D Curated by ChEMBL					Assay Description Inhibition of recombinant human DGAT-1 using 1,2,di(cis-9-octadecenoyl)-sn-glycerol as substrate by Microbeta counter				Bioorg Med Chem Lett 26: 25-32 (2016) Article DOI: 10.1016/j.bmcl.2015.11.046 BindingDB Entry DOI: 10.7270/Q2Z89GDN
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