Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1' and Ligand = 'BDBM50502591'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 (Homo sapiens (Human))	BDBM50502591 (CHEMBL4563171) Show SMILES OC(=O)CC12CCC(CC1)(CO2)c1ccc(cc1)-c1ccc(Nc2nnc(o2)C2CCC2)cn1 |(78.4,-2.43,;77.06,-3.2,;77.06,-4.74,;75.73,-2.43,;74.4,-3.2,;74.39,-4.74,;73.07,-5.51,;71.73,-4.74,;71.72,-3.2,;73.06,-2.43,;72.49,-3.4,;73.57,-4.49,;70.4,-5.51,;70.41,-7.06,;69.08,-7.83,;67.74,-7.06,;67.73,-5.53,;69.06,-4.75,;66.42,-7.84,;65.07,-7.07,;63.75,-7.84,;63.76,-9.38,;62.42,-10.15,;61.09,-9.38,;59.68,-10.02,;58.65,-8.88,;59.42,-7.54,;60.92,-7.86,;58.79,-6.14,;59.34,-4.7,;57.91,-4.15,;57.36,-5.59,;65.09,-10.15,;66.42,-9.38,)| Show InChI InChI=1S/C26H28N4O4/c31-22(32)14-26-12-10-25(11-13-26,16-33-26)19-6-4-17(5-7-19)21-9-8-20(15-27-21)28-24-30-29-23(34-24)18-2-1-3-18/h4-9,15,18H,1-3,10-14,16H2,(H,28,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of recombinant human his-tagged DGAT1 expressed in Sf9 insect cells using oleoyl-CoA and diolein as substrates incubated for 30 mins by LC...				ACS Med Chem Lett 10: 1128-1133 (2019) Article DOI: 10.1021/acsmedchemlett.9b00117 BindingDB Entry DOI: 10.7270/Q28W3HJK
					More data for this Ligand-Target Pair
Diacylglycerol O-acyltransferase 1 (Mus musculus (mouse))	BDBM50502591 (CHEMBL4563171) Show SMILES OC(=O)CC12CCC(CC1)(CO2)c1ccc(cc1)-c1ccc(Nc2nnc(o2)C2CCC2)cn1 |(78.4,-2.43,;77.06,-3.2,;77.06,-4.74,;75.73,-2.43,;74.4,-3.2,;74.39,-4.74,;73.07,-5.51,;71.73,-4.74,;71.72,-3.2,;73.06,-2.43,;72.49,-3.4,;73.57,-4.49,;70.4,-5.51,;70.41,-7.06,;69.08,-7.83,;67.74,-7.06,;67.73,-5.53,;69.06,-4.75,;66.42,-7.84,;65.07,-7.07,;63.75,-7.84,;63.76,-9.38,;62.42,-10.15,;61.09,-9.38,;59.68,-10.02,;58.65,-8.88,;59.42,-7.54,;60.92,-7.86,;58.79,-6.14,;59.34,-4.7,;57.91,-4.15,;57.36,-5.59,;65.09,-10.15,;66.42,-9.38,)| Show InChI InChI=1S/C26H28N4O4/c31-22(32)14-26-12-10-25(11-13-26,16-33-26)19-6-4-17(5-7-19)21-9-8-20(15-27-21)28-24-30-29-23(34-24)18-2-1-3-18/h4-9,15,18H,1-3,10-14,16H2,(H,28,30)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	413	n/a	n/a	n/a	n/a
Novartis Institutes for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of DGAT1 in mouse C2C12 cells assessed as reduction in intracellular triglyceride production incubated for 2 hrs in presence of BSA-comple...				ACS Med Chem Lett 10: 1128-1133 (2019) Article DOI: 10.1021/acsmedchemlett.9b00117 BindingDB Entry DOI: 10.7270/Q28W3HJK
					More data for this Ligand-Target Pair