Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 [89-488]' and Ligand = 'BDBM120753'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 [89-488] (Homo sapiens (Human))	BDBM120753 (US8703761, 1-1) Show SMILES CCOc1ccc(cc1OCC)C(=O)NC(C)(C)C(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1 Show InChI InChI=1S/C31H33N3O4S/c1-5-37-24-18-17-23(20-25(24)38-6-2)28(35)34-31(3,4)29(36)33-30-32-27(22-15-11-8-12-16-22)26(39-30)19-21-13-9-7-10-14-21/h7-18,20H,5-6,19H2,1-4H3,(H,34,35)(H,32,33,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60.5	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
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