Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 [89-488]' and Ligand = 'BDBM120756'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 [89-488] (Homo sapiens (Human))	BDBM120756 (US8703761, 1-28) Show SMILES CC(C)(NC(=O)c1ccc2occc2c1)C(=O)Nc1nc(c(Cc2ccccc2)s1)-c1ccccc1 Show InChI InChI=1S/C29H25N3O3S/c1-29(2,32-26(33)22-13-14-23-21(18-22)15-16-35-23)27(34)31-28-30-25(20-11-7-4-8-12-20)24(36-28)17-19-9-5-3-6-10-19/h3-16,18H,17H2,1-2H3,(H,32,33)(H,30,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
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