Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 [89-488]' and Ligand = 'BDBM120760'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 [89-488] (Homo sapiens (Human))	BDBM120760 (US8703761, 8-2) Show SMILES Cc1ccc(cc1)-c1cc(NC(=O)[C@@H]2CCCN2C(=O)OC(C)(C)C)nc(c1)-c1ccccc1 Show InChI InChI=1S/C28H31N3O3/c1-19-12-14-20(15-13-19)22-17-23(21-9-6-5-7-10-21)29-25(18-22)30-26(32)24-11-8-16-31(24)27(33)34-28(2,3)4/h5-7,9-10,12-15,17-18,24H,8,11,16H2,1-4H3,(H,29,30,32)/t24-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	240	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
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