Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 [89-488]' and Ligand = 'BDBM120763'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Diacylglycerol O-acyltransferase 1 [89-488] (Homo sapiens (Human))	BDBM120763 (US8703761, 14-4) Show SMILES CC(C)(NC(=O)c1ccccn1)C(=O)Nc1nc(-c2ccc(F)cc2)n(Cc2ccccc2)n1 Show InChI InChI=1S/C25H23FN6O2/c1-25(2,30-22(33)20-10-6-7-15-27-20)23(34)29-24-28-21(18-11-13-19(26)14-12-18)32(31-24)16-17-8-4-3-5-9-17/h3-15H,16H2,1-2H3,(H,30,33)(H,29,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	225	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
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