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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Diacylglycerol O-acyltransferase 1 [89-488]' and Ligand = 'BDBM120764'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 1 [89-488]


(Homo sapiens (Human))		BDBM120764
PNG
(US8703761, 14-3)
Show SMILES CN1CCC[C@H]1C(=O)NC(C)(C)C(=O)Nc1nc(-c2ccc(F)cc2)n(Cc2ccccc2)n1
Show InChI InChI=1S/C25H29FN6O2/c1-25(2,29-22(33)20-10-7-15-31(20)3)23(34)28-24-27-21(18-11-13-19(26)14-12-18)32(30-24)16-17-8-5-4-6-9-17/h4-6,8-9,11-14,20H,7,10,15-16H2,1-3H3,(H,29,33)(H,28,30,34)/t20-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.30E+3n/an/an/an/a7.54



Novartis AG

US Patent


Assay Description
The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...

US Patent US8703761 (2014)


BindingDB Entry DOI: 10.7270/Q2057DM1
More data for this
Ligand-Target Pair